Motif ID: FOX{I1,J2}.p2

Z-value: 1.912


Transcription factors associated with FOX{I1,J2}.p2:

Gene SymbolEntrez IDGene Name
FOXI1 2299 forkhead box I1
FOXJ2 55810 forkhead box J2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXJ2chr12_+_80765080.476.4e-02Click!
FOXI1chr5_+_1694654780.185.1e-01Click!


Activity profile for motif FOX{I1,J2}.p2.

activity profile for motif FOX{I1,J2}.p2


Sorted Z-values histogram for motif FOX{I1,J2}.p2

Sorted Z-values for motif FOX{I1,J2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{I1,J2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_19818209 9.986 NM_018993
RIN2
Ras and Rab interactor 2
chr5_+_159368690 5.965 TTC1
tetratricopeptide repeat domain 1
chr5_+_159368733 5.225 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr5_+_159368721 5.183 TTC1
tetratricopeptide repeat domain 1
chr4_+_167013859 4.112 NM_012464
TLL1
tolloid-like 1
chr5_-_59100194 3.642 NM_001197218
PDE4D
phosphodiesterase 4D, cAMP-specific
chr13_-_32757835 3.588 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_+_134800533 3.529 LOC154092
hypothetical LOC154092
chr3_+_11242666 3.446 NM_001098211
HRH1
histamine receptor H1
chr7_+_151284396 3.236 NM_145292
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr5_+_147775652 3.205 FBXO38
F-box protein 38
chr4_+_86968069 3.171 ARHGAP24
Rho GTPase activating protein 24
chr20_+_19863716 3.170 RIN2
Ras and Rab interactor 2
chr9_+_74956601 2.993 ANXA1
annexin A1
chr8_-_108579270 2.876 NM_001146
ANGPT1
angiopoietin 1
chr9_+_74956494 2.762 NM_000700
ANXA1
annexin A1
chr1_-_77457664 2.651 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr6_+_150304813 2.638 NM_025217
ULBP2
UL16 binding protein 2
chr5_-_54317102 2.630 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr1_-_21373816 2.601 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr2_+_201182187 2.564 AOX1
aldehyde oxidase 1
chr9_+_77695334 2.535 NM_001190482
NM_006200
PCSK5

proprotein convertase subtilisin/kexin type 5

chr6_+_153060722 2.534 NM_025107
MYCT1
myc target 1
chr7_+_111908143 2.492 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr21_+_29439768 2.425 C21orf7
chromosome 21 open reading frame 7
chr12_+_27066768 2.389 MED21
mediator complex subunit 21
chr11_+_113672378 2.350 NNMT
nicotinamide N-methyltransferase
chr15_+_65205107 2.344 NM_001145102
SMAD3
SMAD family member 3
chr9_+_129900637 2.341 NM_052901
NM_001006643
SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

chr3_-_170970296 2.337 NM_032487
ARPM1
actin related protein M1
chr3_+_46423682 2.337 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr19_+_57564981 2.326 NM_001145434
ZNF880
zinc finger protein 880
chr9_+_129900590 2.255 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr11_+_113672407 2.238 NNMT
nicotinamide N-methyltransferase
chr7_-_27186400 2.237 NM_153715
HOXA10
homeobox A10
chr1_-_177378801 2.200 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr5_+_55182963 2.171 NM_139017
IL31RA
interleukin 31 receptor A
chr9_+_130719034 2.145 LRRC8A
leucine rich repeat containing 8 family, member A
chr19_-_53305825 2.096 NM_001159322
NM_001159323
NM_003706
PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chr22_+_44828338 2.094


chr12_+_27066749 2.083 NM_004264
MED21
mediator complex subunit 21
chr6_-_56615544 2.072 NM_001723
NM_015548
DST

dystonin

chr19_-_56946911 2.039 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr10_+_86174665 2.033 FAM190B
family with sequence similarity 190, member B
chr1_+_148747110 2.022 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr7_-_87687276 1.974 SRI
sorcin
chr12_-_50871953 1.963 NM_001081492
NM_182507
KRT80

keratin 80

chr12_-_9913199 1.957 CLEC2B
C-type lectin domain family 2, member B
chr2_-_189752575 1.899 NM_000393
COL5A2
collagen, type V, alpha 2
chr7_-_13997574 1.887 NM_001163148
ETV1
ets variant 1
chr16_+_29971971 1.878 NM_000034
ALDOA
aldolase A, fructose-bisphosphate
chr16_+_29971955 1.877 ALDOA
aldolase A, fructose-bisphosphate
chr1_+_157246305 1.864 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr9_-_129381086 1.846 NM_001035534
FAM129B
family with sequence similarity 129, member B
chr7_-_158304062 1.774 ESYT2
extended synaptotagmin-like protein 2
chr17_+_30594192 1.772 NM_144975
SLFN5
schlafen family member 5
chr1_+_84382529 1.750 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_98132898 1.748 NM_001012761
RGMB
RGM domain family, member B
chr6_+_116939500 1.743 NM_153711
FAM26E
family with sequence similarity 26, member E
chr2_-_144991386 1.741 ZEB2
zinc finger E-box binding homeobox 2
chr3_-_115825742 1.727 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr2_+_36777406 1.677 VIT
vitrin
chr12_+_47584159 1.660 NM_033124
CCDC65
coiled-coil domain containing 65
chr9_+_119506274 1.647 NM_138554
TLR4
toll-like receptor 4
chr6_+_121798443 1.645 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr9_+_74956614 1.645 ANXA1
annexin A1
chr5_+_54491702 1.640 NM_001008397
GPX8
glutathione peroxidase 8 (putative)
chr5_-_59100091 1.631 PDE4D
phosphodiesterase 4D, cAMP-specific
chr9_+_119506446 1.630 TLR4
toll-like receptor 4
chr9_+_119506428 1.628 TLR4
toll-like receptor 4
chr12_+_29193399 1.618 FAR2
fatty acyl CoA reductase 2
chr17_-_31219943 1.603 NM_152781
C17orf66
chromosome 17 open reading frame 66
chr3_-_130761967 1.584 PLXND1
plexin D1
chr10_+_71231693 1.578 COL13A1
collagen, type XIII, alpha 1
chr2_-_133145539 1.560 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr5_+_96237923 1.535 ERAP2
endoplasmic reticulum aminopeptidase 2
chr8_-_13416554 1.509 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr2_+_12775814 1.479


chr20_-_29751755 1.477


chr7_-_87687302 1.469 NM_003130
SRI
sorcin
chr1_-_242073094 1.467 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr10_+_71231649 1.457 NM_001130103
NM_080798
NM_080800
NM_080801
NM_080802
NM_080805
COL13A1





collagen, type XIII, alpha 1





chr3_-_184756101 1.427 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr2_-_215998181 1.416 FN1
fibronectin 1
chr6_+_151688327 1.410 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr11_-_101292462 1.401 NM_178127
ANGPTL5
angiopoietin-like 5
chr4_-_89963177 1.377 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr1_+_84540921 1.365 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr2_+_102320148 1.356 NM_003856
IL1RL1
interleukin 1 receptor-like 1
chr16_+_31036474 1.356 NM_032188
NM_182958
MYST1

MYST histone acetyltransferase 1

chr17_+_73886290 1.354 NM_024419
PGS1
phosphatidylglycerophosphate synthase 1
chr9_-_116608113 1.350 NM_005118
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr12_-_9913724 1.345 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr3_-_71196696 1.332 FOXP1
forkhead box P1
chr12_+_55201854 1.325 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr4_+_128773529 1.324 NM_015693
INTU
inturned planar cell polarity effector homolog (Drosophila)
chr3_+_138159396 1.323 NM_144717
IL20RB
interleukin 20 receptor beta
chr3_-_170347019 1.312 NM_001105078
MECOM
MDS1 and EVI1 complex locus
chr1_+_143807748 1.304 NM_004892
SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chr1_+_84536636 1.293 NM_001010971
SAMD13
sterile alpha motif domain containing 13
chr8_+_75066117 1.275 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr10_-_14090459 1.274 FRMD4A
FERM domain containing 4A
chr9_+_5500544 1.273 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr10_-_31328426 1.271 NM_001143769
ZNF438
zinc finger protein 438
chr11_+_65024889 1.263 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr7_-_13995811 1.262 ETV1
ets variant 1
chr9_+_674193 1.258


chr2_+_170044194 1.250 NM_152384
BBS5
Bardet-Biedl syndrome 5
chr3_-_170346760 1.245 NM_001105077
NM_001163999
NM_005241
MECOM


MDS1 and EVI1 complex locus


chr8_+_104452877 1.244 CTHRC1
collagen triple helix repeat containing 1
chr5_+_40877053 1.244 NM_032587
CARD6
caspase recruitment domain family, member 6
chr20_-_14266200 1.235 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr1_+_84382562 1.224 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_-_8695974 1.220 ST5
suppression of tumorigenicity 5
chr9_-_116920232 1.213 NM_002160
TNC
tenascin C
chr9_-_113561613 1.213 NM_001080551
C9orf84
chromosome 9 open reading frame 84
chr15_+_37330176 1.212 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr22_-_43987978 1.211 KIAA0930
KIAA0930
chrX_-_19598912 1.207 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chrX_+_15428820 1.187 NM_203281
BMX
BMX non-receptor tyrosine kinase
chr7_+_28692122 1.175 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr14_+_50096603 1.167 ATL1
atlastin GTPase 1
chr4_-_70861301 1.163 NM_001891
CSN2
casein beta
chr6_-_134540666 1.161 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr12_+_10256682 1.155 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr6_-_112682401 1.153 LAMA4
laminin, alpha 4
chr16_+_27248806 1.148 IL4R
interleukin 4 receptor
chr4_-_186693574 1.145 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr7_-_112513379 1.126 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr8_-_102029997 1.121 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr9_-_16717887 1.115 BNC2
basonuclin 2
chr18_-_21184824 1.112


chr21_+_42492867 1.111 NM_207627
NM_207628
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr11_+_113436438 1.111 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr1_+_242691295 1.102 NM_001130957
NM_173807
C1orf101

chromosome 1 open reading frame 101

chr5_+_159546951 1.100 NM_001130958
FABP6
fatty acid binding protein 6, ileal
chr17_+_55098280 1.088 CLTC
clathrin, heavy chain (Hc)
chr8_+_104452961 1.086 NM_138455
CTHRC1
collagen triple helix repeat containing 1
chr12_+_118100977 1.083 NM_014365
HSPB8
heat shock 22kDa protein 8
chr1_-_67366807 1.080 NM_001013674
C1orf141
chromosome 1 open reading frame 141
chr6_-_112682459 1.080 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr13_+_96726197 1.071 MBNL2
muscleblind-like 2 (Drosophila)
chr1_-_85515174 1.066 NM_003921
BCL10
B-cell CLL/lymphoma 10
chr11_+_57547928 1.055 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr9_+_123123364 1.036 GSN
gelsolin
chr1_-_151866147 1.034 NM_001024213
S100A13
S100 calcium binding protein A13
chr3_-_188946168 1.027 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr2_+_36777336 1.027 NM_001177969
NM_001177970
NM_001177971
NM_001177972
NM_053276
VIT




vitrin




chr1_+_156229686 1.023 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr7_+_150442652 1.022 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr4_+_75393053 1.020 NM_001013442
EPGN
epithelial mitogen homolog (mouse)
chr1_-_171441234 1.020 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr6_-_112682573 1.013 LAMA4
laminin, alpha 4
chr9_-_4290028 1.012 NM_001042413
GLIS3
GLIS family zinc finger 3
chr1_+_99884018 1.002 NM_017734
PALMD
palmdelphin
chr7_+_120415958 0.988 NM_024913
C7orf58
chromosome 7 open reading frame 58
chr6_-_128883125 0.980 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr15_+_73803351 0.969 NM_175881
ODF3L1
outer dense fiber of sperm tails 3-like 1
chr10_+_53744043 0.965 NM_012242
DKK1
dickkopf homolog 1 (Xenopus laevis)
chr9_-_4289915 0.961 GLIS3
GLIS family zinc finger 3
chr9_+_12764988 0.957 NM_203403
C9orf150
chromosome 9 open reading frame 150
chr5_+_34723420 0.940 NM_001145523
RAI14
retinoic acid induced 14
chr12_-_69317441 0.939 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr11_+_59279481 0.938 STX3
syntaxin 3
chr3_-_11598829 0.936 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr9_-_109291575 0.936 KLF4
Kruppel-like factor 4 (gut)
chr4_+_74825138 0.931 NM_000584
IL8
interleukin 8
chrX_-_23955223 0.923 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr2_-_40593074 0.921 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr19_-_42393225 0.918 NM_152279
ZNF585B
zinc finger protein 585B
chr14_+_50096492 0.916 NM_015915
NM_181598
ATL1

atlastin GTPase 1

chr2_-_188021117 0.900 NM_005795
CALCRL
calcitonin receptor-like
chr3_+_137224266 0.892 NM_181897
PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr4_+_124537334 0.892 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr12_-_14929991 0.887 NM_000900
NM_001190839
MGP

matrix Gla protein

chr2_-_207738858 0.883 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr1_-_110735158 0.881 NM_004696
SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr19_-_51319769 0.881 NM_207393
IGFL3
IGF-like family member 3
chr10_+_118177371 0.880 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr22_+_43527101 0.880 NM_001017526
NM_001198726
NM_181335
ARHGAP8


Rho GTPase activating protein 8


chr11_-_121492010 0.870 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr1_+_84382575 0.869 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_+_218768146 0.867 MARK1
MAP/microtubule affinity-regulating kinase 1
chr5_-_119768430 0.863


chr11_+_59279377 0.861 STX3
syntaxin 3
chr18_+_7936885 0.860 PTPRM
protein tyrosine phosphatase, receptor type, M
chr16_+_28993770 0.859 RRN3P2
RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 2
chr3_-_102194938 0.856 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr11_+_111552298 0.852 NM_001037290
BCO2
beta-carotene oxygenase 2
chr10_+_94584449 0.848 NM_001013848
EXOC6
exocyst complex component 6
chrX_+_100361588 0.844 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr1_-_151866367 0.844 NM_001024212
S100A13
S100 calcium binding protein A13
chr7_-_27125738 0.843 NM_030661
HOXA3
homeobox A3
chr9_+_138677197 0.841 NM_201446
NM_016215
EGFL7

EGF-like-domain, multiple 7

chr2_-_225519974 0.840 DOCK10
dedicator of cytokinesis 10
chr11_+_111551417 0.840 NM_031938
BCO2
beta-carotene oxygenase 2
chr21_-_35174742 0.839 RUNX1
runt-related transcription factor 1
chr8_+_67201684 0.838 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr9_-_25668855 0.838 NM_001004125
TUSC1
tumor suppressor candidate 1
chr3_+_87359088 0.838 NM_014043
CHMP2B
chromatin modifying protein 2B

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.70 5.16e-05 GO:2000026 regulation of multicellular organismal development
1.61 1.43e-04 GO:0050793 regulation of developmental process
2.06 3.90e-04 GO:0022603 regulation of anatomical structure morphogenesis
1.68 6.98e-04 GO:0045595 regulation of cell differentiation
2.67 8.54e-04 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.88 1.03e-03 GO:0009968 negative regulation of signal transduction
2.65 1.04e-03 GO:0022604 regulation of cell morphogenesis
1.82 1.87e-03 GO:0023057 negative regulation of signaling
1.34 2.05e-03 GO:0048523 negative regulation of cellular process
1.82 2.05e-03 GO:0010648 negative regulation of cell communication
1.31 4.77e-03 GO:0048519 negative regulation of biological process
1.32 9.23e-03 GO:0048869 cellular developmental process
1.22 9.30e-03 GO:0032502 developmental process
1.40 1.27e-02 GO:0009966 regulation of signal transduction
1.23 1.84e-02 GO:0007275 multicellular organismal development
1.41 2.05e-02 GO:0051239 regulation of multicellular organismal process
1.31 3.12e-02 GO:0030154 cell differentiation
2.89 4.79e-02 GO:0050770 regulation of axonogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.02 3.38e-03 GO:0030427 site of polarized growth
2.95 8.25e-03 GO:0030426 growth cone

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.12 4.58e-02 GO:0005515 protein binding